JAMSTEC > Institute for Extra-cutting-edge Science and Technology Avant-garde Research (X-star) > Super-cutting-edge Grand and Advanced Research (SUGAR) Program > Members > Yutetsu Kuruma

D-SUGAR

Yutetsu Kuruma Ph.D.

Japan Agency for Marine-Earth Science and Technology (JAMSTEC)

RESEARCH INTEREST

  • Synthetic Biology: Construction of Artificial Cell
  • Origin of Life: Constructive study of minimal cellular functions required for the emergence of life
  • Drug Discovery: In vitro synthesis of receptor proteins using cell-free system and binder search

Contact

Super-cutting-edge Grand and Advanced Research Program,
Japan Agency for Marine-Earth Science and Technology (JAMSTEC)
2-15 Natsushima-cho, Yokosuka 237-0061, Japan

EDUCATION

2005
University of Tokyo (Ph.D.)
2002
University of Tokyo (Master)
2000
Teikyo University (Bachelor)

RESEARCH EXPERIENCE

07/2022 to
Present Day
Institute for Extra-cutting-edge Science and Technology Avant-garde Research (X-star), Japan Agency for Marine-Earth Science and Technology (Senior Researcher))
04/2022 to
Present Day
Tokohama City University (YCU) (Visiting Associate Professor)
 
05/2019 to
06/2022
Institute for Extra-cutting-edge Science and Technology Avant-garde Research (X-star), Japan Agency for Marine-Earth Science and Technology (Researcher)
10/2018 to
03/2022
PRESTO, Japan Science and Technology Agency (Researcher)
 
10/2013 to
04/2019
Earth-Life Science Institute, Tokyo Institute of Technology (Project Associate Professor)
01/2008 to
09/2013
Graduate School of Frontier Sciences, University of Tokyo (Project Assistant Professor)
11/2005 to
12/2007
Department of Biology, University of Roma Tre (Research Fellow)

PUBLICATIONS

Google Scholar

SELECTED PUBLICATIONS

  1. Eto, S., Matsumura, R., Shimane, Y., Fujimi, M., Berhanu, S., Kasama, T., and Kuruma, Y., Phospholipid synthesis inside phospholipid membrane vesicles, Communications Biology, 5, 1016, 2022
  2. Shimane, Y. and Kuruma, Y., Rapid and facile preparation of giant vesicles by the droplet transfer method for artificial cell construction, Frontiers in Bioengineering and Biotechnology, 10, 2022
  3. Samuel Berhanu, Takuya Ueda, and Yutetsu Kuruma, Artificial photosynthetic cell producing energy for protein synthesis, Nature Communications, 10, 1325, 2019
  4. Kuruma, Y.* and Ueda, T., The PURE system for the cell-free synthesis of membrane proteins, Nature Protocols 10, 1328–1344, 2015 (*corresponding author)
  5. Matsubayashi, H.*, Kuruma, Y.*, and Ueda, T., In vitro synthesis of the E. coli Sec Translocon from DNA, Angew. Chem. Int. Ed. Engl. 53, 7535-7538, 2014 (*double first authors)
  6. Kuruma, Y., Suzuki, T., Ono, S., Yoshida, M., and Ueda, T., Functional analysis of membraneous Fo-a subunit of F1Fo-ATP synthase by in vitro protein synthesis, Biochem. J., 442, 631–638, 2012
  7. Kuruma Y., Stano P., Ueda T., and Luigi P.L., A synthetic biology approach to the construction of membrane proteins in semi-synthetic minimal cells, Biochem Biophys Acta-Biomem., 1788, 567-574, 2009

SELECTED INVITED LECTURES

  1. 3rd UK-Japan Frontiers of Science Symposium (Fos UK-Jap), “Session Topic: Synthetic Biology Challenges Toward Creating Man-Made Cells”, Nov. 9, 2019
  2. Asian Synthetic Biology Association (ASBA) Meeting, “Artificial photosynthetic cell producing energy for protein synthesis”, Oct. 27, 2019

GRANT (Selected, only as PI)

  1. HFSP, Research Grant, 2020-2023
  2. JST PRESTO, JPMJPR18K
  3. JSPS, Grants-in-Aid for Scientific Research, 16KK0161
  4. JSPS, Grants-in-Aid for Scientific Research, 16H06156
  5. JSPS, Grants-in-Aid for Scientific Research, 16K13096
  6. JSPS, Grants-in-Aid for Scientific Research, 16H00797
  7. JSPS, Grants-in-Aid for Scientific Research, 26119704
  8. JSPS, Grants-in-Aid for Scientific Research, 26103511
  9. JSPS, Grants-in-Aid for Scientific Research, 24119504