Researcher Information
researchmap URL
Research History
- Apr. 2024 - Present
Japan Agency for Marine-Earth Science and Technology, Earth Surface System Research Center, Research Institute for Global Change, 副主任研究員 - Apr. 2023 - Mar. 2024
Waseda University, Faculty of Education and Integrated Arts and Sciences, 嘱託職員 - Jul. 2021 - Mar. 2023
The University of Tokyo, Graduate School of Agricultural and Life Sciences, 特任助教 - Dec. 2019 - Jun. 2021
The University of Tokyo, Graduate School of Agricultural and Life Sciences, 特任研究員 - Dec. 2017 - Nov. 2019
Japan Society for the Promotion of Science, Overseas Research Fellowships - Apr. 2015 - Mar. 2018
Japan Agency for Marine-Earth Science and Technology, 海洋生命理工学研究開発センター, ポストドクトラル研究員 - Jun. 2014 - Mar. 2015
Kyoto University, Graduate School of Science Division of Biological Sciences, 特定研究員 - Apr. 2014 - May 2014
The University of Tokyo, Graduate School of Science, 特任研究員
Research activity information
Papers
- Thomas D Lewin; Tosuke Sakagami; Keisuke Shimizu; Li-Jung Kao; Yi-Ling Chiu; Isabel Jiah-Yih Liao; Mu-En Chen; Kanako Hisata; Kazuyoshi Endo; Noriyuki Satoh; Peter W H Holland; Yue Him Wong; Yi-Jyun Luo
Brachiopod genome unveils the evolution of BMP signalling in bilaterian body patterning.
Nature communications, 12 Mar. 2026
[Reviewed] - Keisuke Shimizu; Katsunori Kimoto; Masahide Wakita; Takenori Sasaki
A window into the effect of ocean acidification on molluscan larval shell development using a quantitative approach
JOURNAL OF MOLLUSCAN STUDIES, Sep. 2025
91, 3
[Reviewed]
Lead, Corresponding - Shigeaki Ohta; Koji Noshita; Katsunori Kimoto; Akito Ishikawa; Hideaki Sato; Keisuke Shimizu; Kazuyoshi Endo
Wnt activation causes shell malformation in lymnaeoidean gastropods
Journal of Molluscan Studies, 26 Feb. 2025
91, 1
[Reviewed] - Shigeaki Ohta; Koji Noshita; Katsunori Kimoto; Akito Ishikawa; Hideaki Sato; Keisuke Shimizu; Kazuyoshi Endo
Possible roles of Wnt in the shell growth of the pond snail Lymnaea stagnalis
Scientific Reports, 03 Nov. 2024
14, 1
[Reviewed] - Keisuke Shimizu; Lumi Negishi; Hitoshi Kurumizaka; Michio Suzuki
Diversification of von Willebrand Factor A and Chitin-Binding Domains in Pif/BMSPs Among Mollusks
Journal of Molecular Evolution, 12 Jun. 2024
[Reviewed]
Lead - Lingxiao Zhu; Keisuke Shimizu; Hiroyuki Kintsu; Lumi Negishi; Zehua Zheng; Hitoshi Kurumizaka; Shohei Sakuda; Isao Kuriyama; Takashi Atsumi; Kaoru Maeyama; Kiyohito Nagai; Michiyo Kawabata; Hisanori Kohtsuka; Toru Miura; Yoshitaka Oka; Shinsuke Ifuku; Koji Nagata; Michio Suzuki
Structural and functional analyses of chitinolytic enzymes in the nacreous layer of Pinctada fucata
BIOCHEMICAL ENGINEERING JOURNAL, Feb. 2023
191
[Reviewed] - Keisuke Shimizu; Lumi Negishi; Takumi Ito; Shogo Touma; Toshie Matsumoto; Masahiko Awaji; Hitoshi Kurumizaka; Kazutoshi Yoshitake; Shigeharu Kinoshita; Shuichi Asakawa; Michio Suzuki
Evolution of nacre- and prisms-related shell matrix proteins in the pen shell, Atrina pectinata.
Comparative biochemistry and physiology. Part D, Genomics & proteomics, Dec. 2022
44, 101025, 101025
[Reviewed]
Lead - Keisuke Shimizu; Takeshi Takeuchi; Lumi Negishi; Hitoshi Kurumizaka; Isao Kuriyama; Kazuyoshi Endo; Michio Suzuki
Evolution of EGF-like and Zona pellucida domains containing shell matrix proteins in mollusks.
Molecular biology and evolution, 07 Jul. 2022
39, 7
[Reviewed]
Lead - Asuka Sentoku; Keisuke Shimizu; Tsubasa Naka; Yuki Tokuda
Dimorphic life cycle through transverse division in burrowing hard coral Deltocyathoides orientalis.
Scientific reports, 07 Jun. 2022
12, 1, 9359, 9359
[Reviewed] - Keisuke Shimizu; Koji Noshita; Katsunori Kimoto; Takenori Sasaki
Phylogeography and shell morphology of the pelagic snail Limacina helicina in the Okhotsk Sea and western North Pacific
MARINE BIODIVERSITY, Apr. 2021
51, 2
[Reviewed]
Lead, Corresponding - Keisuke Shimizu; Hiroyuki Kintsu; Masahiko Awaji; Toshie Matumoto; Michio Suzuki
Evolution of Biomineralization Genes in the Prismatic Layer of the Pen Shell Atrina pectinata.
Journal of molecular evolution, Dec. 2020
88, 10, 742, 758
[Reviewed]
Lead - Davin H. E. Setiamarga; Kazuki Hirota; Masa-aki Yoshida; Yusuke Takeda; Keiji Kito; Keisuke Shimizu; Yukinobu Isowa; Kazuho Ikeo; Takenori Sasaki; Kazuyoshi Endo
Hydrophilic Shell Matrix Proteins ofNautilus pompiliusand The Identification of a Core Set of Conchiferan Domains
16 Nov. 2020
[Reviewed] - Shihori Iwamoto; Keisuke Shimizu; Lumi Negishi; Nobuo Suzuki; Koji Nagata; Michio Suzuki
Characterization of the chalky layer-derived EGF-like domain-containing protein (CgELC) in the pacific oyster, Crassostrea gigas.
Journal of structural biology, 01 Oct. 2020
212, 1, 107594, 107594
[Reviewed]
Lead - Akito Ishikawa; Keisuke Shimizu; Yukinobu Isowa; Takeshi Takeuchi; Ran Zhao; Keiji Kito; Manabu Fujie; Noriyuki Satoh; Kazuyoshi Endo
Functional shell matrix proteins tentatively identified by asymmetric snail shell morphology.
Scientific reports, 17 Jun. 2020
10, 1, 9768, 9768
[Reviewed] - Keisuke Shimizu; Kazuki Kimura; Yukinobu Isowa; Kenshiro Oshima; Makiko Ishikawa; Hiroyuki Kagi; Keiji Kito; Masahira Hattori; Satoshi Chiba; Kazuyoshi Endo
Insights into the Evolution of Shells and Love Darts of Land Snails Revealed from Their Matrix Proteins.
Genome biology and evolution, 01 Feb. 2019
11, 2, 380, 397
[Reviewed] - Keisuke Shimizu; Katsunori Kimoto; Koji Noshita; Masahide Wakita; Tetsuichi Fujiki; Takenori Sasaki
Phylogeography of the pelagic snail Limacina helicina (Gastropoda: Thecosomata) in the subarctic western North Pacific
JOURNAL OF MOLLUSCAN STUDIES, Feb. 2018
84, 30, 37
[Reviewed] - Keisuke Shimizu; Yi-Jyun Luo; Noriyuki Satoh; Kazuyoshi Endo
Possible co-option of engrailed during brachiopod and mollusc shell development.
Biology letters, Aug. 2017
13, 8
[Reviewed] - Koji Noshita; Keisuke Shimizu; Takenori Sasaki
Geometric analysis and estimation of the growth rate gradient on gastropod shells.
Journal of theoretical biology, 21 Jan. 2016
389, 11, 9
[Reviewed] - KEISUKE Shimizu, Kazuyoshi Endo
Evo-Devo of spiral shell growth in gastropods
Proceeding of the 3rd International Symposium on Biological Shape Analysis, 2015
130, 137
[Reviewed]
Lead, Corresponding - Davin H E Setiamarga; Keisuke Shimizu; Junpei Kuroda; Kengo Inamura; Kei Sato; Yukinobu Isowa; Makiko Ishikawa; Reo Maeda; Tomoyuki Nakano; Tomoko Yamakawa; Ryo Hatori; Akira Ishio; Kayo Kaneko; Kenjiroo Matsumoto; Isao Sarashina; Shinnosuke Teruya; Ran Zhao; Nori Satoh; Takenori Sasaki; Kenji Matsuno; Kazuyoshi Endo
An in-silico genomic survey to annotate genes coding for early development-relevant signaling molecules in the pearl oyster, Pinctada fucata.
Zoological science, Oct. 2013
30, 10, 877, 88
[Reviewed] - Keisuke Shimizu; Minoru Iijima; Davin He Setiamarga; Isao Sarashina; Tetsuhiro Kudoh; Takahiro Asami; Edi Gittenberger; Kazuyoshi Endo
Left-right asymmetric expression of dpp in the mantle of gastropods correlates with asymmetric shell coiling.
EvoDevo, 28 May 2013
4, 1, 15, 15
[Reviewed]
Lead, Corresponding - Keisuke Shimizu; Isao Sarashina; Hiroyuki Kagi; Kazuyoshi Endo
Possible functions of Dpp in gastropod shell formation and shell coiling.
Development genes and evolution, Jun. 2011
221, 2, 59, 68
[Reviewed]
Presentations
- Keisuke SHIMIZU; Katsunori KIMOTO; Masahide Wakita
Effects of ocean acidification on larval shell development in Scallop
The International Symposium on the Okhotsk Sea & Polar Oceans, 17 Feb. 2026 - 清水啓介 (海洋研究開発機構)
浮遊性有孔虫の遺伝子解析の基盤構築
CREST「海洋カーボン」第３回領域会議, 27 Nov. 2025 - 清水啓介 (海洋研究開発機構)
100 年後の海では貝が殻を作りにくくなる? ~酸性化が進んだ“海の 脅威”~
第21回むつ海洋・環境科学シンポジウム, 19 Nov. 2025 - 清水啓介 (海洋研究開発機構)、木元克典 (海洋研究開発機構)、脇田昌英 (海洋研究開発機構)、遊佐貴志 (青森県産業技術センター)
二枚貝幼生の貝殻成長の定量解析 -酸性化実験を例に-
第20回バイオミネラリゼーションワークショップ, 13 Nov. 2025 - 清水啓介 (海洋研究開発機構)
海洋酸性化による貝殻形成への影響
海洋酸性化適応プロジェクトワークショップ, 30 Oct. 2025, [Invited] - 吉原桃果 (琉球大学); 千徳明日香(琉球大学); 長澤祥太郎(琉球大学); 清水啓介(JAMSTEC)
ミドリシャミセンガイに残された付着痕の形成過程と保存性の解析
第96回日本動物学会 (2025), 05 Sep. 2025 - 清水啓介 (海洋研究開発機構); 木元克典 (海洋研究開発機構); 松野孝平 (北海道大学); 山口篤 (北海道大学); 野下浩司 (九州大学)
有殻翼足類ミジンウキマイマイの分子系統地理
第96回日本動物学会 (2025), 05 Sep. 2025
Media Coverage
- 酸性化する海 未来の姿か
日本経済新聞, In Focus 環境アップデート, 02 Apr. 2026, Paper - 陸奥湾ホタテクライシス(3) 最新の取り組み
NHK青森放送局, あっぷるワイド, 25 Mar. 2026, Media report - 紋別沖の環境変化を探る
民友新聞, 21 Mar. 2026, Paper - ホタテの人工採苗試験に着手 陸奥湾産再生目指し／野辺地町漁協
デーリー東北, 04 Mar. 2026, Paper - 陸奥湾ホタテ、青森・野辺地町漁協が人工種苗の実験開始
河北新報, 04 Mar. 2026, Paper - ホタテ再生へ人工採苗に挑戦
東奥日報, 04 Mar. 2026, Paper - 「まずは陸奥湾で再生を」野辺地町漁協がホタテ人工採苗に挑む 高水温やタイ食害で9割へい死
RAB青森放送, 03 Mar. 2026, Media report - 湾内初ホタテの人工種苗 野辺地町漁協「まず陸奥湾で再生」
ABA青森朝日放送, 03 Mar. 2026, Media report - 「まず陸奥湾で再生しないといけない」大量死した青森県の「陸奥湾ホタテ」の復活に向けた挑戦
ATV青森テレビ, 03 Mar. 2026, Media report - ホタテ、「海の酸性化」で成長妨げられ将来減少の可能性 実験で判明
朝日新聞, 28 Dec. 2025, Paper - CO2増加、貝類もピンチ
朝日新聞, 13 Nov. 2025, Paper - 「100年後、海で貝は育たない?」海洋機構の青森での研究で浮かんだ懸念とは
河北新報, 16 Oct. 2025, Media report - 「海の酸性化で貝が育たなくなる？ 100年後には「骨粗鬆症」状態に」
朝日新聞, 16 Oct. 2025, Paper - 未来の海では貝が育たない？ ―酸性化が進んだ"海の脅威"を数値化し、貝類幼生への影響を予測―
海洋研究開発機構, 18 Sep. 2025, Internet
